Blood in your urine is one of those symptoms that stops you cold. And it should. The types of hematuria break into two main categories: microscopic hematuria (blood you can’t see without a lab test) and gross hematuria (blood that turns your urine pink, red, or brown). Roughly 6.5% of the population deals with hematuria at some point, and the difference between these types isn’t just academic. It changes your risk level, the tests you’ll need, and how fast your doctor should be moving.
Hematuria is the medical term for blood in your urine, and it’s grouped by visibility: microscopic hematuria is only detected through urinalysis, while gross hematuria is visible to the naked eye. Each type carries a different risk profile for serious conditions like bladder cancer, kidney stones, and infections.
This article won’t cover every rare genetic kidney condition. It focuses on what matters for the average person who just got a test result back or noticed something off in the toilet: the types, the risk, and what to do next.

What Is Microscopic Hematuria?
Microscopic hematuria means there are red blood cells in your urine, but not enough to see. The standard definition is more than 3 red blood cells per high-power field (RBCs/HPF) on a microscopy exam. You’d never know it was there without a urinalysis.
Here’s what most articles get wrong about microscopic hematuria: they tell you it’s “usually nothing.” That framing is outdated. The 2025 AUA/SUFU Microhematuria Guideline, the first major update since 2020, now uses a risk-stratification model. Your RBC count, age, smoking history, and gender all factor into whether you’re low-risk, intermediate-risk, or high-risk.
The numbers tell a more grounded story. Low-risk microscopic hematuria carries a malignancy rate of just 0–0.4%. Intermediate-risk cases run 0.2–3.1%. High-risk cases hit 1.3–6.3%. Those aren’t huge percentages, but if you’re in that high-risk bracket, a 1-in-16 chance of cancer isn’t something you shrug off.
I’ve seen patients who had microscopic hematuria flagged on a routine physical, got told “it’s probably nothing,” and didn’t follow up for two years. By then, what was a treatable bladder lesion became something far worse. The single most expensive mistake in hematuria evaluation is ignoring the microscopic kind.
So if your doctor finds blood during a routine urine test, ask a direct question: “What’s my risk category per the AUA tables?” If they can’t answer that, you need a urologist.

What Does Gross Hematuria Look Like?
Gross hematuria (also called frank hematuria) is the type you notice yourself. Your urine turns pink, red, cola-colored, or dark brown. Sometimes you’ll see small clots.
What surprises most people is how little blood it takes. Just 1 milliliter, roughly a fifth of a teaspoon, can change the color of your urine. So the shade doesn’t tell you how much blood is actually there. A pale pink toilet bowl and a dark red one can both signal the same underlying problem.
Gross hematuria is taken seriously almost by default. And for good reason. The malignancy risk sits around 11%, according to 2025 AUA data. That means about 1 in 9 people with visible blood in their urine have an underlying cancer. This type almost always triggers an urgent evaluation, including cystoscopy and imaging.
One thing patients don’t realize: volume of blood doesn’t predict severity. A small amount of blood from a bladder tumor is far more dangerous than a large amount from a kidney stone that’s already passing. The color of your urine is a signal to act, not a diagnostic tool.
How Does Exercise-Induced Hematuria Happen?
Jogger’s hematuria is a real (and surprisingly common) type that shows up after intense or prolonged physical activity. Long-distance runners, cyclists, and even military recruits in basic training deal with it.
The mechanism is mostly mechanical. Repeated impact causes the bladder walls to slap together when the bladder is partially empty, damaging small blood vessels. In runners, the foot-strike itself sends shock waves up through the body. Dehydration makes it worse because concentrated urine is more irritating to the bladder lining.
Here’s the catch. Exercise-induced hematuria is a diagnosis of exclusion. You can’t assume your bloody urine is from running until a urologist has ruled out everything else. I’ve worked with practices where patients self-diagnosed “runner’s hematuria” for months before someone finally ordered a cystoscopy and found early-stage bladder cancer. The exercise was coincidental.
If it happens once after a marathon, it’s probably benign. If it keeps happening, get it checked.

What Causes the Different Types of Hematuria?
Beyond the visible-vs-invisible distinction, hematuria is often classified by its source. This is where the diagnostic work really begins.
- Infections are the most common culprit. Urinary tract infections, kidney infections (pyelonephritis), and bladder inflammation (cystitis) all cause blood in urine. In premenopausal women, UTIs are the number-one reason for hematuria. But here’s a problem that urologists complain about constantly: primary care providers will treat “UTIs” for years based on symptoms alone, never sending a urine culture. If cultures are negative and blood persists, the infection theory falls apart. And the real cause keeps hiding.
- Kidney and bladder stones are the second most frequent trigger. Calcium stones, uric acid stones, and staghorn calculi all scrape the urinary tract lining and produce blood. The pain is usually the giveaway, but small stones can cause painless hematuria, too.
- Prostate conditions matter for men over 50. Benign prostatic hyperplasia (BPH) and prostatitis both cause hematuria. So does prostate cancer, though that’s less common as an isolated symptom.
- Kidney diseases like IgA nephropathy and thin basement membrane disease cause microscopic hematuria that can persist for years. These are often benign, but they still need monitoring because some progress to chronic kidney disease.
- Cancers of the bladder, kidney, ureter, and prostate are the highest-stakes causes. Bladder cancer is the one most associated with hematuria. In fact, blood in the urine is the first symptom in roughly 80–90% of bladder cancer cases.
- Iatrogenic causes (meaning doctor-caused) include recent catheterization, kidney biopsy, and procedures like extracorporeal shockwave lithotripsy for stones. These are usually self-limiting and expected.

What’s Not Actually Hematuria?
Not every red toilet bowl means blood. Several things mimic hematuria and send people into unnecessary panic.
Beets are the classic offender. Betanin, the pigment in beets, turns urine pink or red in roughly 10–14% of people (a harmless condition called beeturia). Medications like rifampicin and phenazopyridine (the bladder pain reliever that comes in those bright orange pills) do the same. Myoglobin from severe muscle breakdown and porphyrins from certain metabolic disorders also discolor urine.
A simple urinalysis separates real hematuria from look-alikes. If the dipstick is positive but microscopy shows no red blood cells, it’s likely myoglobinuria or a false positive. The dipstick test alone has a relatively high false-positive rate, which is why microscopy confirmation matters.

How Is Hematuria Evaluated in 2026?
The workup depends on the type and your risk category. Here’s what it looks like in practice.
| Evaluation Level | What’s Included | Approximate Cash Cost |
| Basic screen | Repeat urinalysis + office visit | $150–$300 |
| Standard workup | Above + cystoscopy | $500–$1,500 |
| Full evaluation | Above + CT urogram or biomarkers | $2,000+ |
Cystoscopy, a thin camera inserted into the bladder, remains the gold standard for ruling out bladder cancer. It’s a quick office procedure (usually under 5 minutes) with minimal discomfort for most patients. Many people fear it far more than it deserves. A urologist who specializes in these evaluations does them daily.
The 2025 AUA guidelines now also discuss urine-based tumor markers as a supplement, not a replacement, for cystoscopy. These biomarker tests are gaining traction, but they’re not validated enough yet to stand alone in low-risk patients.
One contrarian point worth making: CT urograms get ordered too often and too early. Many primary care providers order a CT before even referring to urology. That adds cost, radiation exposure, and delays. For most patients, cystoscopy plus a renal ultrasound covers the bases without the CT.

When Should You See a Urologist for Blood in Urine?
Any visible blood warrants a call to your doctor the same day. For microscopic hematuria found on a routine test, ask for a repeat urinalysis first. If blood shows up again, you need a referral to a urologist.
Questions to ask during that visit: What’s my risk category? Will cystoscopy be done in-office or referred out? Does my family history of kidney or bladder cancer change the approach? Should I repeat testing in 6 or 12 months if everything looks clear now?
Persistent microscopic hematuria raises malignancy risk compared to a single positive test that clears, according to data presented at the 2025 SUO Annual Meeting. A single negative retest carried a 0.07% malignancy risk, while a persistent blood test jumped to 0.35%. Small numbers, but a fivefold difference.
The types of hematuria matter because they change the urgency, the workup, and the cost. Gross hematuria gets you fast-tracked. Microscopic hematuria gets risk-stratified. And exercise-induced hematuria gets a pass only after everything else is ruled out. If you’re dealing with any of them, the worst move is waiting. Practices that can help connect you with the right specialist faster.
Frequently Asked Questions
What is the difference between gross and microscopic hematuria?
Gross hematuria means you can see blood in your urine. It turns the toilet water pink, red, or brown. Microscopic hematuria is only found through a lab urinalysis showing more than 3 red blood cells per high-power field. Gross hematuria carries about an 11% malignancy risk, while microscopic hematuria risk is stratified from 0–0.4% (low) to 1.3–6.3% (high) based on 2025 AUA guidelines.
Does microscopic hematuria always mean cancer?
No. The large majority of microscopic hematuria cases are benign. Low-risk patients have a malignancy rate of just 0–0.4%. But persistent microscopic hematuria still needs a risk-stratified evaluation, because even a small percentage becomes meaningful across thousands of patients. Don’t skip follow-up.
How many red blood cells per HPF counts as hematuria?
The standard threshold is more than 3 RBCs per high-power field on microscopy. The 2025 AUA guidelines further break this down: 3–10 RBCs/HPF is low-count, 11–25 is intermediate, and over 25 is high-count. Higher counts push you into higher risk categories that call for cystoscopy.
Can exercise cause blood in urine?
Yes. Jogger’s hematuria happens when repeated physical impact damages small blood vessels in the bladder. It’s common in long-distance runners and typically resolves within 72 hours of rest. But exercise-related hematuria is a diagnosis of exclusion. A urologist needs to rule out other causes first, especially if it keeps recurring.
What types of hematuria require a cystoscopy?
Gross hematuria almost always requires cystoscopy. For microscopic hematuria, the 2025 AUA guidelines recommend cystoscopy for intermediate- and high-risk patients. Low-risk patients may defer cystoscopy through shared decision-making with their urologist, but repeat urinalysis within 6–12 months is still recommended.
Can foods or medications make urine look like blood?
Yes. Beets turn urine pink or red in about 10–14% of people. Medications like rifampicin and phenazopyridine also cause red-orange discoloration. A urinalysis with microscopy confirms whether actual red blood cells are present or if it’s a harmless pigment.
When should I see a urologist about blood in my urine?
Any visible blood in your urine warrants a same-day call to your doctor. For microscopic hematuria found on a routine test, a repeat urinalysis should come first. If blood appears again, a urology referral is the next step. Waiting is the most common and most costly mistake patients make with hematuria.

Dr. Carolyn Fronczak is the founder and Medical Director of Modern Urology Colorado. She is board certified by the American Board of Urology, with expertise in both men’s and women’s urologic care. She completed her medical degree at the University of Colorado School of Medicine and her surgical training at the University of Nebraska Medical Center. Dr. Fronczak has treated thousands of patients in the Boulder/Denver area.