Xiaflex in Boulder, CO

FDA approved nonsurgical treatment for Peyronie's disease that targets the plaque causing penile curvature.

Understanding Peyronie's Disease

Peyronie’s disease affects more men than many realize, yet it remains one of the most difficult conditions to discuss. Scar tissue, called plaque, forms inside the penis and causes curvature, pain during erections, and often significant emotional distress. The condition can impact relationships, self confidence, and quality of life in profound ways. Understanding what causes Peyronie’s disease and knowing effective treatment options exist is the first step toward reclaiming normal function and peace of mind.

The plaque that characterizes Peyronie’s disease develops in the tunica albuginea, the fibrous sheath surrounding the erectile chambers of the penis. When this tissue becomes scarred and inelastic, it doesn’t stretch properly during erection. The normal tissue expands while the scarred area remains rigid, creating a bend or curve. Some men also experience painful erections, shortening of the penis, or an hourglass shape. In more severe cases, the curvature makes intercourse difficult or impossible.

The exact cause of Peyronie’s disease isn’t fully understood, though most experts believe it develops after repeated minor injuries during sexual activity, athletic activities, or accidents. These small traumas trigger an abnormal healing response in some men, leading to excessive scar tissue formation. Risk factors include genetics, age over 40, smoking, certain connective tissue disorders, and previous pelvic surgery or radiation. Many men feel isolated or embarrassed by the condition, but Peyronie’s disease is more common than most realize, affecting up to 10 percent of men.

For years, treatment options were limited. Oral medications showed minimal effectiveness. Surgery carried risks of scarring, erectile dysfunction, and penile shortening. Many doctors recommended simply waiting to see if the condition improved on its own. Modern Urology now offers Xiaflex in Boulder, CO, the first and only FDA approved nonsurgical treatment proven to reduce penile curvature in men with Peyronie’s disease. This breakthrough therapy provides hope for men who previously faced limited options.

Dr. Fronczak has extensive experience treating Peyronie’s disease with Xiaflex. She understands the sensitive nature of this condition and approaches every consultation with professionalism, discretion, and genuine compassion. Men appreciate her straightforward explanations, realistic expectations about results, and commitment to helping them regain normal function and confidence.

Xiaflex is a proven treatment for penile curvature and does not result in penile shortening.

If your penile curvature is causing difficulty with erections and difficulty with intercourse, there is an excellent in-office treatment with a medication called Xiaflex.

Fronczak is certified to provide Xiaflex treatments safely and has had great success with these treatments in significantly reducing penile curvature.

 

  • Xiaflex involves injection of a medication that will soften the scar tissue and post injection “modeling” straightens the penis.
  • Xiaflex treatment involves up to four treatments that are spaced 6 weeks apart.
  • Xiaflex is covered by most insurance companies.

If you have penile curvature that is causing you distress or concern, please make an appointment with Dr. Fronczak to discuss your evaluation and options.

The providers at Modern Urology team up with our patients.  We listen, we include our patients in the decision-making process, and we educate them on their condition.  This approach leads to finding the root cause of the urologic problem and success at preventing future urologic problems.  

We understand that many patients do not want, nor need surgery.  The providers at Modern Urology will approach our patient’s urologic problems with conservative treatment options before recommending surgical procedures, as appropriate. 

Modern Urology offers the most advanced evaluation and treatment options.  From using the highest quality diagnostic equipment to offering nitrous oxide for anxious patients, we provide superior urologic care in a relaxed pleasant environment. 

How Xiaflex Works

Xiaflex represents a significant breakthrough in treating Peyronie’s disease. The medication contains collagenase clostridium histolyticum, an enzyme that specifically targets and breaks down the collagen fibers forming the Peyronie’s plaque. By dissolving this scar tissue over time, Xiaflex allows the penis to straighten during erection. The treatment combines injections with penile modeling exercises to achieve optimal results.

The Science Behind Xiaflex

Xiaflex works by enzymatically breaking the bonds between collagen molecules that form the rigid Peyronie’s plaque, gradually dissolving the scar tissue that prevents normal stretching during erection. This targeted approach affects only the plaque itself, leaving normal surrounding tissue, blood vessels, and nerves intact.

 

Proven Clinical Results

Clinical trials involving over 1,000 men showed that Xiaflex reduced penile curvature by an average of 34 percent compared to just 18 percent with placebo. Beyond physical straightening, men reported decreased bother from the condition, improved ability to have intercourse, and enhanced quality of life.

The Injection Protocol

Each treatment cycle consists of two Xiaflex injections given one to three days apart, with Dr. Fronczak precisely targeting the densest portion of the plaque causing maximum deformity. Most men require up to four treatment cycles spaced six weeks apart, and you must avoid sexual activity for at least two weeks after each cycle while the plaque is temporarily weakened.

 

Modeling and Home Exercises

One to three days after the second injection, Dr. Fronczak performs a penile modeling procedure, applying gentle pressure to stretch and elongate the treated plaque for about 30 seconds, repeated three times. You’ll then perform gentle penile stretching activities three times daily for six weeks, as compliance with these home exercises significantly improves outcomes.

Take the First Step Toward Improvement

Living with Peyronie’s disease affects more than physical function. It impacts confidence, relationships, and emotional wellbeing. Modern Urology offers Xiaflex in Boulder, CO, providing men with a proven, FDA approved solution. Contact us today to schedule your confidential consultation with Dr. Fronczak.

Treatment Process and Timeline

Understanding what to expect during Xiaflex treatment helps men feel prepared and confident. The process follows a specific protocol designed to maximize results while ensuring safety. Most men require multiple treatment cycles to achieve desired improvement, with each cycle separated by six weeks. The complete treatment timeline spans several months, but many men notice gradual improvement throughout the process.

Your journey begins with a comprehensive evaluation. Dr. Fronczak takes a detailed medical history, including when you first noticed the curvature, whether you experience pain, and how the condition affects your life. She performs a physical examination to assess the plaque’s size, location, and density. This examination happens with the penis in a non erect state, allowing her to feel the scar tissue and determine if Xiaflex is appropriate for your situation.

Xiaflex works best for men with a palpable plaque and curvature of at least 30 degrees. Dr. Fronczak may take measurements or photographs to document your baseline curvature, providing objective data to track improvement. She explains the treatment process, sets realistic expectations about results, discusses potential side effects, and answers all your questions. Many men feel immediate relief simply knowing an effective treatment exists and having a doctor who understands their concerns.

Some men benefit from bringing a partner to this consultation. Peyronie’s disease affects relationships, and having your partner understand the treatment process can provide valuable support. Dr. Fronczak welcomes partners and creates an environment where both people feel comfortable asking questions.

Each Xiaflex treatment cycle follows a structured timeline. You receive the first injection on day one. The injection takes just minutes and happens in the office. Dr. Fronczak carefully identifies the point of maximum curvature and injects Xiaflex directly into the plaque. Most men describe the injection as briefly uncomfortable but tolerable.

One to three days later, you return for the second injection of the cycle. Again, the medication is injected into the plaque following the same careful technique. After this second injection, you avoid sexual activity for at least two weeks to allow proper healing. This abstinence period is crucial for safety, as the plaque is temporarily weakened during the breakdown process.

One to three days after the second injection, you return for the penile modeling procedure. Dr. Fronczak stretches the plaque by applying firm pressure, essentially helping the penis straighten as the scar tissue softens. This procedure is performed on the non erect penis and takes about 30 seconds, repeated three times. While potentially uncomfortable, most men tolerate it well knowing it enhances results.

After each treatment cycle, you perform home penile stretching exercises three times daily for six weeks. Dr. Fronczak demonstrates the proper technique, which involves gently stretching the penis in the direction opposite to the curve. These exercises take just minutes but play a vital role in maintaining and improving the straightening achieved through Xiaflex.

You may also perform gentle bending exercises if you get an erection without sexual activity. These additional stretches help train the tissue as it heals. Compliance with home exercises significantly impacts your final results. Men who diligently perform their exercises typically achieve better outcomes than those who don’t.

 

Most men require up to four treatment cycles to achieve maximum improvement. Each cycle is separated by approximately six weeks, allowing adequate healing time between treatments. During these intervals between cycles, you continue home exercises and may notice progressive improvement in curvature. The cumulative effect of multiple treatment cycles produces the best results.

Not every man needs all four cycles. Dr. Fronczak assesses your progress after each cycle and discusses whether additional treatment would provide further benefit. Some men achieve satisfactory improvement after two or three cycles. The decision to continue treatment is made collaboratively based on your goals, progress achieved, and response to therapy.

You Might Benefit from Xiaflex If

  • You have a noticeable curve in your penis that appeared over time
  • You experience pain during erections that affects your quality of life
  • Your penile curvature makes intercourse difficult or impossible
  • You can feel a hard lump or band of tissue inside your penis
  • You’ve avoided intimacy because of embarrassment about the appearance
  • Your curvature measures at least 30 degrees during erection
  • You want to avoid surgery but need effective treatment
  • You’ve been told to just wait and see if it improves on its own
  • Your relationship is suffering due to sexual difficulties related to curvature
  • You’re looking for the only FDA approved nonsurgical treatment available
A man being examined by a urologist
Board Certified by the American Board of Urology
Member of American Urologic Society
Member of South Central Section of the American Urologic Society
Member of Rocky Mountain Urologic Society
Member of Boulder County Medical Society (past board member)

Serving Boulder's Community

Modern Urology proudly provides Xiaflex in Boulder, CO, serving men throughout the area who struggle with Peyronie’s disease. From the bustling Pearl Street Mall to the serene trails at Chautauqua Park, Boulder represents a community that values health, wellness, and quality of life. When conditions like Peyronie’s disease threaten these values, Dr. Fronczak is here to help.

Men in Boulder appreciate having access to the most advanced treatment options without traveling to Denver or beyond. Whether you live in North Boulder near Ideal Market, South Boulder, Table Mesa, or surrounding communities, Modern Urology provides convenient access to specialized men’s health care. We understand that discussing conditions like Peyronie’s disease requires privacy and discretion, qualities we prioritize in every aspect of our practice.

Dr. Fronczak has chosen to practice in Boulder because she values this community’s progressive approach to healthcare. Men here ask informed questions, research treatment options, and want to understand the science behind recommendations. Our practice philosophy aligns perfectly with these values, providing detailed explanations, evidence based treatments, and respect for your autonomy in healthcare decisions.

Convenient Location

Easily accessible from Boulder via US-36, serving patients throughout Weld County and the greater Denver Boulder metro area

Flexible Scheduling

We offer appointment times that work with your schedule, including options for men who work full time in Boulder’s tech and research sectors

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Frequently Asked Questions

How long does Xiaflex treatment take to work?

Xiaflex works gradually over multiple treatment cycles. Each cycle consists of two injections given one to three days apart, followed by penile modeling and six weeks of home exercises. Most men require up to four treatment cycles spaced six weeks apart, meaning the complete treatment timeline spans several months. You may notice progressive improvement throughout treatment, but maximum results typically appear after completing all recommended cycles. The gradual timeline allows the plaque to break down safely while your body adjusts to the changes.

Is Xiaflex treatment painful?

Most men find Xiaflex treatment manageable. The injections cause brief discomfort as the needle enters the plaque, but the procedure takes just minutes. Common side effects include bruising, swelling, and pain at the injection site, which typically resolve within one to two weeks. The penile modeling procedure can be uncomfortable but is brief. Pain or discomfort generally decreases with subsequent treatment cycles as men know what to expect. Dr. Fronczak uses careful injection technique to minimize discomfort and provides guidance on managing side effects at home.

Does insurance cover Xiaflex for Peyronie’s disease?

Many insurance plans cover Xiaflex for Peyronie’s disease, as it’s recognized as a significant medical condition affecting function and quality of life. Coverage varies by insurance provider and specific plan. The Xiaflex Copay Assistance Program can cover up to $1,200 per vial for eligible patients with commercial insurance, and most eligible patients pay little to nothing out of pocket. Our office staff verifies your insurance benefits before treatment and helps you understand costs. We’re committed to making this proven treatment accessible to men who need it.

What are the risks of Xiaflex treatment?

Like any medical treatment, Xiaflex carries some risks. The most serious potential complication is penile fracture, which occurred in 0.5 percent of men in clinical trials. This risk is why you must avoid sexual activity for at least two weeks after each treatment cycle while the plaque is temporarily weakened. Other potential risks include allergic reactions, though these are uncommon. Most side effects like bruising, swelling, and pain at the injection site are temporary and resolve within one to two weeks. Dr. Fronczak discusses all risks during your consultation and monitors you carefully throughout treatment.

Am I a good candidate for Xiaflex?

Good candidates for Xiaflex include men with Peyronie’s disease who have a palpable plaque and penile curvature of at least 30 degrees. The condition should be stable rather than actively changing. Men seeking to avoid surgery but wanting effective treatment often benefit most. You should not receive Xiaflex if the plaque involves your urethra or if you have allergies to the medication. Dr. Fronczak performs a thorough evaluation to determine if Xiaflex is appropriate for your specific situation, considering your plaque characteristics, curvature severity, overall health, and treatment goals.

We Accept Most Major Insurance

Reclaim Confidence and Function

Peyronie’s disease affects too many men who suffer in silence, unaware that effective treatment exists. Modern Urology offers Xiaflex in Boulder, CO, the only FDA approved nonsurgical option proven to reduce penile curvature and improve quality of life. Dr. Fronczak combines specialized expertise in men’s health with genuine compassion for the sensitive nature of this condition. Whether you’re experiencing pain, struggling with intercourse, or simply want to address the curvature before it worsens, we’re here to help.

Contact Modern Urology today to schedule your confidential consultation and take the first step toward reclaiming the confidence and normal function you deserve with Xiaflex in Boulder, CO.