Xiaflex In Colorado Springs, CO
The FDA-Approved Treatment for Peyronie's Disease
What Is Peyronie's Disease?
Peyronie’s disease is a condition in which fibrous scar tissue, called plaque, develops inside the penis. This plaque causes the penis to curve or bend during erections, which can range from mild to severe. The curvature can make erections painful and make sexual intercourse difficult or impossible depending on the degree of the bend.
Peyronie’s disease affects an estimated 6 to 10 percent of adult men in the United States, though many cases go unreported because men feel embarrassed or assume nothing can be done. The plaque develops gradually and differs from the natural shape variations that are normal among men. Without treatment, there is almost a 50 percent chance that the curvature will worsen during the first year after symptoms appear, according to natural history studies. Spontaneous improvement is rare.
If you have noticed a curve in your erect penis, felt a firm bump or band of tissue under the skin of the shaft, or experienced pain during erections, these may be signs of Peyronie’s disease. The condition is not caused by anything you did wrong. It is a medical condition with effective treatment options.
How Xiaflex Treats Peyronie's Disease
Xiaflex (collagenase clostridium histolyticum) is the first and only FDA-approved non-surgical treatment for Peyronie’s disease. It works by breaking down the collagen that makes up the Peyronie’s plaque. When injected directly into the plaque, the enzymes in Xiaflex weaken and dissolve the scar tissue, allowing the penis to gradually straighten over the course of treatment.
Unlike surgery, Xiaflex does not require incisions, general anesthesia, or recovery from an operation. Clinical studies demonstrated an average curvature reduction of 34 percent in men treated with Xiaflex combined with daily penile stretching and straightening exercises. Importantly, Xiaflex has been shown to reduce curvature without causing penile shortening, a concern that many men have when considering treatment for Peyronie’s disease.
Xiaflex has been in clinical use for Peyronie’s disease since its FDA approval in 2013, giving physicians and patients more than a decade of real-world treatment experience.
Who Is a Candidate for Xiaflex?
Xiaflex is appropriate for adult men with stable Peyronie’s disease who have a plaque that can be felt under the skin and a penile curvature of at least 30 degrees at the start of treatment. Dr. Fronczak evaluates each patient individually to determine whether Xiaflex is the right approach based on the location, severity, and stability of the curvature.
You may not be a candidate for Xiaflex if the plaque involves the urethra, if the curvature is still actively changing (acute phase), if there is extensive calcification at the site of maximum curvature, or if you have a known allergy to collagenase. Dr. Fronczak discusses all of these factors during your consultation so there are no surprises before treatment begins.
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The Xiaflex Treatment Protocol: What to Expect
Xiaflex treatment for Peyronie’s disease involves up to four treatment cycles, spaced approximately six weeks apart. Each cycle follows a structured two-part process of injection and modeling designed to progressively reduce the curvature.
Part one: The injection
Dr. Fronczak injects Xiaflex directly into the Peyronie’s plaque in the office. The injection targets the scar tissue responsible for the curvature. Each treatment cycle includes two injection visits separated by one to three days.
Part two: Penile modeling
One to three days after the second injection of each cycle, Dr. Fronczak performs an in-office penile modeling procedure. This involves gentle manual stretching and straightening of the penis to help break down the softened plaque and encourage the penis to straighten. You will also be instructed to perform gentle stretching and straightening exercises at home daily for up to six weeks between cycles.
If the curvature improves to less than 15 degrees after any cycle, additional cycles may not be needed. Dr. Fronczak monitors your progress throughout treatment and adjusts the plan based on your individual response.
Why Dr. Fronczak for Xiaflex in Colorado Springs, CO
Xiaflex is available only through a restricted program called the REMS (Risk Evaluation and Mitigation Strategy) program. Only urologists who have completed the required REMS training and have experience with penile injection procedures are certified to administer it. Dr. Fronczak is a certified Xiaflex provider who has successfully treated numerous men with Peyronie’s disease using this protocol.
Dr. Fronczak is board certified by the American Board of Urology and brings more than a decade of clinical experience to every consultation. She earned her medical degree from the University of Colorado School of Medicine and completed her surgical training at the University of Nebraska Medical Center. She is a member of the American Urologic Society and the Rocky Mountain Urologic Society.
Her approach to Xiaflex treatment goes beyond simply administering injections. She evaluates the full clinical picture, discusses realistic expectations, explains modeling technique in detail, and ensures that you feel prepared and informed before the first injection.
What to Know Before and After Treatment
Xiaflex treatment requires some important precautions. Dr. Fronczak will discuss these thoroughly during your consultation, but here is a general overview of what to expect before and after your injections.
Before treatment, let Dr. Fronczak know if you take blood thinners or have a bleeding disorder, as these may affect your eligibility. Inform her of any allergies, particularly to collagenase products.
After each injection cycle, common temporary side effects include swelling, bruising, and tenderness at the injection site or along the shaft. These typically resolve within a few weeks. In rare cases, more serious reactions such as a penile hematoma or, very rarely, corporal rupture (penile fracture) can occur. Dr. Fronczak will explain the signs to watch for and what to do if you experience them.
You should avoid sexual intercourse for at least four weeks after each injection to allow healing and reduce the risk of complications. Dr. Fronczak will provide specific guidance on when it is safe to resume intimate activity.
Xiaflex in Colorado Springs, CO: Serving the Front Range
Modern Urology serves men with Peyronie’s disease from Colorado Springs, Monument, Fountain, Palmer Lake, Castle Rock, Woodland Park, Black Forest, Falcon, and communities throughout the Pikes Peak region and Front Range. Our clinic is conveniently located at 4943 State Hwy 52 Suite 180, Frederick, CO 80514, making it easily accessible for patients throughout the surrounding areas.
Men choose Modern Urology for Xiaflex treatment because Dr. Fronczak is a REMS-certified, board certified urologist who takes the time to evaluate each case individually, explain the treatment clearly, and guide patients through every step of the process. The entire treatment is performed in a private, comfortable office setting with nitrous oxide available for relaxation during procedures.
Frequently Asked Questions
What is Xiaflex and how does it work?
Xiaflex is the only FDA-approved non-surgical treatment for Peyronie’s disease. It contains enzymes (collagenase clostridium histolyticum) that break down the collagen fibers in Peyronie’s plaque. When injected directly into the scar tissue that causes penile curvature, Xiaflex weakens the plaque over a series of treatment cycles. Combined with in-office and at-home penile modeling exercises, this process gradually reduces the curve and restores a more natural penile shape.
Does Xiaflex cause the penis to get shorter?
No. One of the advantages of Xiaflex over some surgical approaches is that it does not result in penile shortening. Dr. Fronczak has had significant success using Xiaflex to reduce curvature while preserving penile length, which is a primary concern for many men considering treatment for Peyronie’s disease.
How many Xiaflex treatments will I need?
The Xiaflex protocol allows for up to four treatment cycles spaced six weeks apart. Each cycle includes two injections and an in-office modeling session. Some men see meaningful improvement after fewer cycles. If the curvature decreases to less than 15 degrees, additional cycles are typically not needed. Dr. Fronczak tracks your progress and adjusts the plan accordingly.
Is Xiaflex painful?
You may experience temporary swelling, bruising, and tenderness at the injection site after each treatment, which usually resolves within a few weeks. Nitrous oxide is available during the procedure at Modern Urology to help you stay relaxed and comfortable. Most men find the discomfort manageable with over-the-counter pain relief and find that the improvement in curvature is well worth the temporary side effects.
Can I have sex during Xiaflex treatment?
You should avoid sexual intercourse for at least four weeks after each Xiaflex injection to allow the treatment area to heal and reduce the risk of complications. Dr. Fronczak will provide specific guidance on when it is safe to resume intimate activity based on your individual healing progress.
Does my insurance cover Xiaflex?
Most major insurance plans cover Xiaflex when it is prescribed for Peyronie’s disease. A co-pay assistance program from the manufacturer may also be available. Modern Urology’s staff will help verify your coverage and handle prior authorization before treatment begins so you know what to expect.